Suppression of phosphoenolpyruvate carboxykinase gene expression by reduced endogenous glutathione level
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چکیده
منابع مشابه
Multihormonal Regulation of Phosphoenolpyruvate Carboxykinase Gene Transcription
We used a nuclear RNA transcript elongation assay to show that cAMP analogs and dexamethasone cause a selective increase of transcription of the P-enolpyruvate carboxykinase gene in H4IIE hepatoma cells. 8-(4-~hlorophenylthio)-cAMP increased transcription within 5 min and the maximal rate, generally 10-15fold above the basal rate, was attained by 30 min. This increase was of sufficient magnitud...
متن کاملsupplementary analysis of phosphoenolpyruvate carboxykinase gene expression in developing seeds of chickpea
studies on the genes contributing to the seed filling in chickpea and its protein content might be valuable in engineering plants with seeds of a higher nutritional value. a gene of interest is phosphoenolpyruvate carboxykinase (pepck), encoding a protein with a substantial role in the gluconeogenesis pathway. in the present study, the protein content (percentage) was measured in a number of cu...
متن کاملHepatic phosphoenolpyruvate carboxykinase gene expression is not repressed by dietary carbohydrates in rainbow trout (Oncorhynchus mykiss).
Phosphoenolpyruvate carboxykinase (PEPCK) is a rate-limiting enzyme in hepatic gluconeogenesis and therefore plays a central role in glucose homeostasis. The aim of this study was to analyse the nutritional regulation of PEPCK gene expression in rainbow trout (Oncorhynchus mykiss), which are known to use dietary carbohydrates poorly. A full-length hepatic PEPCK cDNA (2637 base pairs with one op...
متن کاملAspects of the control of phosphoenolpyruvate carboxykinase gene transcription.
Published, JBC Papers in Press, July 27, 2009, DOI 10.1074/jbc.R109.040535 Jianqi Yang, Lea Reshef, Hanoch Cassuto, Gabriela Aleman, and Richard W. Hanson From the Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106-4936 and the Department of Biochemistry and Molecular Biology, Hebrew University-Hadassah School of Medicine, Jerusalem 991120, Israel
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
سال: 2007
ISSN: 0925-4439
DOI: 10.1016/j.bbadis.2007.10.001